On October 21, Professor Liu Changmeng's team at Beijing Institute of Technology published research in Nature, pioneering a new single-crystal additive manufacturing method called "micro-melt-pool unsteady pulsating growth." This method enables direct growth of titanium alloy single crystals up to meter-scale in height and centimeter-scale in diameter from a polycrystalline substrate without the need for seed crystals. A Nature News & Views expert commentary was published alongside the paper. The team validated the method using Ti-6Al-4V single crystals, whose creep resistance is orders of magnitude higher than that of forgings and additively manufactured polycrystalline structures. The method is based on a wire-arc additive manufacturing platform, with raw material costs far lower than powder-based routes, and is also applicable to single crystals of refractory metals such as tungsten, molybdenum, and niobium. This achievement advances crystal structure control in metal additive manufacturing from polycrystalline equiaxed/columnar structures to controllable single-crystal growth, opening new manufacturing and repair pathways for high-temperature load-bearing components such as aero-engine blades. It represents an important additive manufacturing publication by a Chinese institution in Nature this year; its wire-arc route offers a contrast to powder-bed routes in specific large-size single-crystal scenarios. Value for powder buyers: ① If single-crystal additive manufacturing moves toward industrialization, its raw material form will primarily be wire, with no direct short-term replacement for the conventional atomized powder market—it can be tracked as a watch item for now; ② Monitor the impact on demand structure for specialty powders (nickel-based single-crystal master alloy powders) if the method extends to superalloy single crystals; ③ Top-journal publications are often followed by industrialization teams and fundraising activities—engagement with the team's supply chain needs can be initiated early.