In August 2026, the journal *Additive Manufacturing*—a leading publication in the field—featured a paper by researchers from the Institute of Metal Research, Chinese Academy of Sciences, titled "Mesoscale Microstructure-Dependent Stress Rupture Behavior and Service Adaptation Mechanism of L-PBF Additively Manufactured Nickel-Based Superalloy" (DOI: 10.1016/j.addma.2026.105348). The first author is Peng Wang, with contributing authors including Jingjing Liang, Jinguo Li, Yizhou Zhou, and others. The study investigates the stress rupture behavior of laser powder bed fusion (L-PBF) nickel-based superalloys under high-temperature service conditions. It reveals how mesoscale microstructural features—such as grain orientation, sub-grain boundaries, and stray grains—govern stress rupture life and fracture modes, establishing a microstructure–property–service adaptation relationship. These findings provide a theoretical framework for evaluating the creep and rupture performance of additively manufactured superalloy components used in hot-section parts like turbine disks and blades. Nickel-based superalloy powders represent the highest-value, most technically challenging segment of metal additive manufacturing materials. Their creep/rupture performance directly determines whether aero-engine and gas-turbine hot-section components can enter service. Research linking mesoscale microstructure to rupture behavior offers a key theoretical anchor for optimizing the entire chain—from powder to process to post-treatment. Value for powder buyers: (1) Quality assessment of L-PBF superalloy powders (e.g., Inconel 718, GH3536, K477) should place greater emphasis on batch-to-batch consistency of mesoscale microstructure; factors such as particle size distribution, oxygen content, and sphericity—which influence stray grain and sub-grain boundary formation—will become key procurement technical indicators. (2) The process–microstructure control strategies outlined in this paper can support joint development with powder suppliers of specialty grades with improved crack resistance and high rupture performance. (3) It is advisable to monitor the process validation and data accumulation efforts of leading domestic superalloy powder suppliers in this area.