A joint research team from Xi'an Jiaotong University has established a quantitative framework linking cooling rate, solute redistribution, and heterogeneous α precipitation. By integrating phase-field simulations, computational fluid dynamics modeling, and experiments, the study found that at an appropriate cooling rate (about 4.0×10⁵ K/s), significant intragranular solute gradients arise during solidification, triggering spatially heterogeneous α precipitation—coarse α phases form within solute-rich grain interiors via classical nucleation and growth, while fine α phases form near grain boundaries via pseudo-spinodal decomposition. Validated in PBF-LB/M Ti-Mo alloys with optimized parameters, nanoindentation shows that heterogeneous regions achieve higher elastic modulus while maintaining similar hardness. This structural design is expected to simultaneously enhance strength, toughness, and fatigue performance, offering new pathways for microstructural regulation of customized high-performance titanium alloy components.