Published online on November 4 in Materials and Manufacturing Processes (Xiao Yan of Guangzhou College of Technology and Business; Yao Dongming and Wan Chuanling of Changchun University of Technology, et al.): For the PBF-LB processing of Ti-15Nb elemental powder blends, the team developed a process optimization workflow driven by X-CT defect data. Evaluating 41 parameter sets and 18 tensile conditions, they found that maximum pore diameter (Dmax) is strongly correlated with elongation. A six-objective desirability function selected the optimal parameter set, which was reproduced in an independent build with high density, high strength, high ductility, and low porosity risk. The elemental powder blending route can significantly reduce raw material costs compared with pre-alloyed spherical powders, but achieving uniformity and controlling defects are more difficult. The study introduces X-CT non-destructive testing into a closed process-defect-performance loop, establishing a quantifiable porosity-mechanical property relationship for parts printed from blended powders. This work provides a data-driven method for process control in the elemental powder blending route and offers a reusable optimization paradigm for additive manufacturing process development of medical beta titanium alloys (Ti-15Nb is an aluminum- and vanadium-free biocompatible system). Replacing pre-alloyed powders with elemental blends can lower costs, but buyers evaluating blended powder solutions should also pay attention to CT defect characterization and process stability verification methods.